Abstract

A template condensation of 3,3’- diaminobenzidine with benzil and dimethyl ortho- phenylenediamine in the presence of Cu(II), Ni(II) and VO(II) resulted in the formation of tetradentate macrocyclic Schiff base binuclear complexes of the type [M₂ L.X] and [M₂ L]. X₂ (where, X= 2ClO₄^-, CH₃COO- and 2SO₄^-). Structural characterization of the complexes were achieved by several physicochemical methods, namely elemental analysis, electronic spectra, infrared, EPR, cyclic voltammetry, molar conductivity and magnetic susceptibility measurements. A square planar binuclear structure was proposed for the perchlorate anions in Cu(II) and Ni(II) complexes. Whereas the square pyramidal environment around the VO(II) center. The Schiff base complexes were investigated for antibacterial and antifungal properties of gram-positive bacteria (taphylococcus auerus), gram-negative bacteria (pseudomonas fluorescens) and fungi (Aspergillus fumigates) were used in this study to assess their antimicrobial properties. The results showed that this skeletal framework exhibit marked potency as antimicrobial agents.

Keywords

Tetradentate macrocyclic Schiff base, EPR, Cyclic voltametry, Square-pyramidal, Aspergillus fumigates