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  • Chem Sci Trans., 2013, 2(S1),  pp S295-S301  

    DOI:10.7598/cst2013.443

    Research Article

    Investigation of Various Green Chemistry Approaches for the Efficient Synthesis of Dialkyl-1, 4-dihydro-4-(substituted phenyl)-2, 6-dimethylpyridine-3, 5-dicarboxylate

  • PRABHJOT KAUR and RAJESH K. SINGH
  • Pharmaceutical Chemistry Division, Shivalik College of Pharmacy, Nangal, Distt-Rupnagar- 140126, Punjab, India
  • Abstract

    A green chemistry methodologies were utilized for the efficient synthesis of Hantzsch 1,4-dihydropyridine derivatives by one-pot multicomponent reaction of substituted aldehydes, ethyl/methyl acetoacetate and ammonium acetate by conventional, microwave, solvent-free and ultrasonication techniques. All the compounds were characterized by TLC, FT-IR, 1H NMR and elemental studies.

    Keywords

    Green chemistry, 1,4-Dihydropyridine, Conventional, Microwave, Ultrasonic, Solvent-free

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