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  • Chem Sci Trans., 2013, 2(1),  pp 329-335  

    DOI:10.7598/cst2013.260

    Research Article

    Synthesis of New Derivatives of Resveratrol and to Explore its Potential Health Benefits

  • E. F. AL-JUMAILY, Z. A. SHAFIQ and R. I. AL-BAYATI
  • Institute of Genetic Engineering & Biotechnology for Postgraduate Studies, University of Baghdad, Iraq
    Chemistry Department, College of Science, Al-Mustansiriya University, Iraq
  • Abstract

    The aim of this study was extracting and purifying resveratrol from skin black grapevine. The synthesis of new derivatives from purified resveratrol was employed through out a series of reactions. The synthesized compounds are: (E)-2,2'-(5-(4-(carboxymethoxy)styryl)-1,3-phenylene) bis (oxy) diacetic acid (derivative 1); (E)- 5-(4-(3-chloropropanyloxy)styryl)-1,3-phenylene) bis(3-chloro-propanoate (derivative 2); 5-(4-(4-hydrazinylbutanoyloxy) styryl)-1,3-phenylenebis(4-hydrazinyl-butanoate) (derivative 3) and 5-(4-(4-(2-(benzo[d]thiazol-2-yl)hydrazinyl) butanoyloxy) styryl)-1,3-phenylene bis(4-(2-(benzo[d]thiazol-2-yl) hydrazinyl)butanoate) (derivative 4) respectively. The synthesized compounds were studied for exploring potential health benefits.

    Keywords

    Reveratrol, Reveratrol derivatives, Synthesis, Health Benefits

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