• image 01
    Volume 1, No.1, 2012
  • image 02
    Volume 1, No.2, 2012
  • image 01
    Volume 1, No.3, 2012
  • image 02
    Volume 2, No.1, 2013
  • image 02
    Volume 2, No.2, 2013
  • image 02
    Volume 2, No.S1, 2013
  • image 02
    Volume 2, No.3, 2013
  • image 02
    Volume 2, No.4, 2013
  • image 02
    Volume 3, No.1, 2014
  • image 02
    Volume 3, No.2, 2014
  • Volume 3, No3
    Volume 3, No.3, 2014
  • Volume 3, No4
    Volume 3, No.4, 2014
  • Volume 4, No1
    Volume 4, No.1, 2015
  • Volume 4, No2
    Volume 4, No.2, 2015
  • Volume 4, No3
    Volume 4, No.3, 2015
  • Volume 4, No4
    Volume 4, No.4, 2015
  • Volume 5, No1
    Volume 5, No.1, 2016
  • image 01
  • image 02
  • Login|Register
  • Chem Sci Trans., 2013, 2(1),  pp 61-64  

    DOI:10.7598/cst2013.284

    Research Article

    Spectrophotometric Determination of Valacyclovir in Pharmaceutical Formulations

  • G. SRIHARI, N. RAMI REDDY, K. NAGARAJA SETTY and I.E. CHAKRAVARTHI
  • Department of Chemistry, S.B.S.Y.M. Degree College, Kurnool (Dt), Andhra Pradesh, India
    Department of Chemistry, Government College for Men, Kurnool (Dt), Andhra Pradesh, India
    Department of Chemistry, Rayalaseema University, Kurnool (Dt), Andhra Pradesh, India
  • Abstract

    A simple spectrophotometric method has been developed for the estimation of valacyclovir in pharmaceutical preparations. The method is based on the reaction of the valacyclovir with methanolic solution of para dimethyl amino benzaldehyde (PDAB) in acidic condition producing Schiff base having absorption maximum at 400 nm. Beer’s law is obeyed in the concentration of 50-250 µg/mL of valacyclovir. Statistical analysis proves that the proposed method is reproducible and selective for the estimation of valacyclovir in bulk drug and in its tablet dosage form.

    Keywords

    Spctrophotometry, Valacyclovir, para dimethyl amino benzaldehyde, Formulations

    This article has been viwed 2842 times

      

    Citations for this article 5

      

    Download Citations