Indexing Metadata
Chemical and Biological Studies on
Some Pregnane Derivatives |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | Chemical and Biological Studies on
Some Pregnane Derivatives |
| 2 | Creator | Author's name, affiliation, country | N. M. ABD EL-SALAM1* and G. A. AHMED2
1 Department of Natural Sciences, Riyadh Community College, King Saud University, P.O.Box 2455, Riyadh-11451, Saudi Arabia
2Chemistry Department, Faculty of Science, Zagazig University, Egypt |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Pyrimidine, Pyrazoline, Isoxazoline |
| 4 | Description | Abstract | Reaction of the pregnane derivatives (1), (2), (3) and (4) with hydrazines, afforded the pyrazoline derivatives, (5a,b), (6a,b), (7a, b) and (8a,b) respectively, compound (1) and (3) reacted with urea and thiourea and give pyrimidine and pyrimidinethione derivatives (9a,b) and (10a,b) respectively. Also, compound (1) reacted with hydroxylamine hydrochloride and guanidine carbonate in refluxing ethanol and yield the isoxazole derivative (11) and the aminopyrimidine (12). Evaluation of the biological activity of the synthesized compounds, were carried and they had a significant effects as antibiotics and gram positive bacteria and gram negative bacteria. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 1 , Number (1), (2012) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
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