Indexing Metadata
A Simple Spectrophotometric Estimation of Tramadol Hydrochloride in Pharmaceutical Formulations |
| DUBLIN | CORE | METADATA ITEM | METADATA FOR THIS DOCUMENT |
| 1 | Title | Title of Document | A Simple Spectrophotometric Estimation of Tramadol Hydrochloride in Pharmaceutical Formulations |
| 2 | Creator | Author's name, affiliation, country | K. NAGARAJA SETTY*, T. RAMACHARa, I. E. CHAKRAVARTHYb
and K. PRABHAVATHIc
*Department of Chemistry, Government Degree College for Men, Kurnool-518002, India
aDepartment of Chemistry, G. Pulla Reddy Engineering College, Kurnool-518002, India
b Department of Chemistry, Rayalaseema University, Kurnool-518002, A.P, India
cDepartment of Chemistry, S. B. S.Y. M. Degree College, Kurnool-518004, A.P, India |
| 3 | Subject | Dicipline(s) | Chemical Science |
| 3 | Subject | Keywords | Ultraviolet-visible spectrophotometry, Tramadol hydrochloride, Wool fast Blue, (WFB), Formulations |
| 4 | Description | Abstract | A simple, accurate, rapid and sensitive spectrophotometric method has been developed for the determination of tramadol hydrochloride in pharmaceutical formulations. The method was based on the formation of chloroform extractable complex of tramadol hydrochloride with wool fast blue, which shows absorbance maxima at 590 nm against the reagent blank treated similarly. The method obeys Beer's law in the concentration ranges of 50-250 µg/mL. Validation studies are statistically significant as all the statistical parameters are within the acceptance range (% RSD< 2.0 and S.D. < 2.0) for both accuracy and precision study. High recovery and low % RSD reveals the reliability of the method for quantitative study of the proposed method in tablet formulation. The proposed method is simple, rapid accurate, precise, reproducible and economic and can be used for routine quantitative analysis of tramadol hydrochloride in pure and tablet dosage form. |
| 5 | Publishers | Organizing agency, location | WWW Publications, India |
| 6 | Contributor | Sponsor(s) | - |
| 7 | Date | Date (YYYY-MM-DD) | - |
| 8 | Type | Status & genre | Peer-reviewed Article |
| 8 | Type | Type | |
| 9 | Formate | File Formate | PDF |
| 10 | Identifier | Uniform Resource Identifier | Click Here |
| 10 | Identifier | Digital Object Identifier | |
| 11 | Source | Journal/conference title; vol., no. (Year) | Chemical Science Transactions, Volume 1 , Number (2), (2012) |
| 12 | Lanuguage | English=en | en |
| 13 | Relation | Supp.files | |
| 14 | Coverage | | - |
| 15 | Copyright | Copyright and permissions | |
Chemical Science Transactions | Chem Sci Trans | CST | Online Chemistry Journal | Open Access
|
